Work

Thoracic endovascular aortic repair for advanced esophageal cancer invading the aorta: A prognosis analysis among 124 patients

Year: 2025

Type: article

Abstract: Objectives: Advanced esophageal cancer invading the aorta is considered an unresectable disease with a poor prognosis. We evaluated the clinical impact of elective thoracic endovascular aortic repair implantation on the prognosis of such patients. Methods: We retrospectively evaluated patients with advanced esophageal cancer and aortic invasion who underwent thoracic endovascular aortic repair to assess its prognostic impact under multimodal treatment. Results: < .001). Under multivariate analysis, compared with patients who underwent salvage thoracic endovascular aortic repair, those who received elective thoracic endovascular aortic repair with and without esophagectomy had reduced odds ratios of mortality (95% CI) of 0.21 (0.11-0.41) and 0.38 (0.20-0.74), respectively. Conclusions: Compared with salvage thoracic endovascular aortic repair, elective thoracic endovascular aortic repair implanted after diagnosis for esophageal cancer with aortic invasion is associated with improved overall survival. It provides the opportunity for esophagectomy, further prolonging survival compared with those without esophagectomy.

Source: JTCVS Open

DOI: 10.1016/j.xjon.2025.09.021