Work

Development and evaluation of a liposomal gel containing Ajuga bracteosa for topical treatment of gout

Year: 2025

Type: article

Abstract: This study evaluates a liposomal gel containing Ajuga bracteosa leaf extract for the topical treatment of gout and inflammation. The extract was encapsulated using the thin-film hydration method and incorporated into a carbopol gel base. The formulation was assessed for physicochemical properties, drug release, and anti-inflammatory activity using the carrageenan-induced paw edema model in rats. The liposomal gel significantly reduced paw edema, joint swelling, and pain compared to controls, indicating improved bioavailability and therapeutic potential. This suggests it may offer a promising herbal alternative for localized gout and inflammation management.

Source: International Journal of Pharmaceutical Research and Development

DOI: 10.33545/26646862.2025.v7.i2c.186

Authors: Dev Prakash Dahiya, Anchal Sankhyan, Manjula Verma, Taranpreet ., Samriti .

Institution: Abhilashi University

Language: English

Topic: Advancements in Transdermal Drug Delivery

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4414440277