Work

Leiomyosarcoma of the left kidney with renal vein and inferior vena cava tumor thrombus

Year: 2025

Type: article

Abstract: Primary renal leiomyosarcoma (PRLMS) are rare, aggressive smooth muscle tumors, and vascular involvement with tumor thrombus is especially uncommon. We present a case of a 66-year-old male with hematuria and abdominal pain found to have a 10.5 cm left renal mass with thrombus extending into the renal vein and inferior vena cava (IVC). The patient underwent open radical nephrectomy with IVC thrombectomy. Histopathology confirmed grade 2 leiomyosarcoma with negative surgical margins, The patient recovered uneventfully and remains disease-free five months postoperatively, highlighting the important of complete resection.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2025.103221

Authors: Austin Erickson, Aleksander Druck, Andreas Karachristos, Trushar Patel

Institution: University of South Florida

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,160