Work

Intradural calcifying pseudoneoplasm of the neuraxis in the lumbosacral canal: Two case reports and review of the literature

Year: 2025

Type: article

Abstract: Background Calcifying pseudoneoplasms of the neuraxis (CAPNON) are benign and slowly growing fibro-osseous lesions of the nervous system. Methods We report two rare cases of spinal CAPNON and provide a literature review. Results A 33-year-old woman with back pain underwent lumbar magnetic resonance imaging (MRI), revealing a large intradural mass (1.5 × 0.9 × 10.6cm 3 ) at L2-S1. Postoperative MRI scan performed 3 years after surgery confirmed no recurrence. A 64-year-old woman with lower limb numbness and gait instability underwent lumbar MRI, revealing an L3 intradural mass (1.1 × 0.3 × 1.6cm 3 ). Lower limb numbness were resolved after surgery during 1 year follow-up. Conclusion Accurate recognition of CAPNON is essential to guide appropriate surgical intervention due to its favorable prognosis. In these situations, complete resection and radiological follow-up are highly recommended.

Source: International Journal of Surgery Case Reports

DOI: 10.1016/j.ijscr.2025.111966

Authors: Shuo Han, Guang-Ming Wang, Da-Wei Dai, Dan-Feng Zhang

Institutions: Shanghai Changzheng Hospital, Renji Hospital

Language: English

Topic: Bone Tumor Diagnosis and Treatments

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,090