Work

Dual fungal endocarditis in a pediatric dialysis patient: First case of Aspergillus flavus and Candida parapsilosis co-infection

Year: 2025

Type: article

Abstract: We report the first pediatric case of dual fungal infective endocarditis (IE) caused by Aspergillus flavus and Candida parapsilosis in a dialysis-dependent child from a conflict-affected region. Diagnosis was supported by galactomannan monitoring, histopathology, and molecular sequencing. Management required early surgery and prolonged dual antifungal therapy. Despite the rarity and severity of such coinfections, the patient survived. This case highlights the importance of early recognition, multidisciplinary care, and aggressive treatment in pediatric fungal IE.

Source: Medical Mycology Case Reports

DOI: 10.1016/j.mmcr.2025.100735

Authors: Tasneem Shamsi Basha, Amina Bakro, Hari Pankaj Vanam, Akela Ghazawi, Areej AlGhamdi, Fatima Al Dhaheri

Institution: Shaikh Khalifa Medical City

Language: English

Topic: Infective Endocarditis Diagnosis and Management

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $650