Work

Perspectives in clinical microbiology for combating multi-drug resistant bacterial infections

Year: 2025

Type: article

Abstract: Multidrug-resistant bacterial infections are a major global threat, exacerbated by globalization and poor sanitation. Bacteria develop resistance through mechanisms like enzymatic degradation, efflux pumps, and horizontal gene transfer. Rapid diagnostics and artificial intelligence are crucial for overcoming the limitations of traditional culture methods. Combating this issue requires novel therapeutic strategies, such as bacteriophages, antimicrobial peptides, and microbiome-based therapies. Ultimately, proper antibiotic use, increased research, and global multidisciplinary cooperation are essential to address this complex challenge.

Source: Frontiers in Cellular and Infection Microbiology

DOI: 10.3389/fcimb.2025.1695284

Authors: André Mauricio de Oliveira, Camila Prósperi de Castro

Institution: Federal Center for Technological Education of Minas Gerais

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801