Work

The influence of dynamic cerebral autoregulation efficiency on its directional sensitivity

Year: 2025

Type: article

Abstract: Dynamic cerebral autoregulation (dCA) is more efficient for increases in mean arterial blood pressure (MAP) compared with reductions in MAP. We found that directional sensitivity of dCA is dependent on its efficiency, with differences depending on sex and age. In older women, strength of directional sensitivity (DS CA ) is not affected by dCA efficiency, but in younger women, DS CA decreases with dCA efficiency, whereas in both younger and older men, DS CA strength increases with dCA efficiency.

Source: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

DOI: 10.1152/ajpregu.00140.2025

Authors: Ronney B. Panerai, Aaron Davies, Victoria J. Haunton, Abdulaziz Alshehri, Emmanouil Katsogridakis, Lucy C. Beishon, Thompson G. Robinson, Jatinder S. Minhas

Institutions: University of Leicester, Glenfield Hospital, British Heart Foundation, NIHR Leicester Biomedical Research Centre, Najran University

Language: English

Topic: Heart Rate Variability and Autonomic Control

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: UK Research and Innovation, Stroke Association, Najran University, Engineering and Physical Sciences Research Council, NIHR Leicester Biomedical Research Centre

Awards: G5073120814, G5326330789, Diversity in blood flow control of the brain: moving from individualized modelling towards personalized treatment of the injured brain., G8602646507

OpenAlex ID: W4414446102

FWCI: 2.594

Cites: 63

Cited by: 4

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