Recurrent adult-type granulosa cell tumor of the ovary: A case report
Year: 2025
Type: article
Study design: Case Report
Abstract: Adult ovarian granulosa cell tumors (AGCTs) are among the most common types of gonadal sex cord-stromal tumors. This pathological entity is generally associated with a favorable prognosis but only accounts for about 2–5% of all malignant ovarian tumors. Disease stage is the most important prognostic factor, with patients diagnosed at an early stage exhibiting a good prognosis. Surgery remains the cornerstone of treatment, both for primary and recurrent cases, while chemotherapy is typically reserved for inoperable or advanced progressive situations. Despite treatment, about one-third of patients experience relapse or progression within 4–7 years, and approximately 50% of these cases result in mortality. We report a case of recurrent AGCT occurring three years after initial surgery and chemotherapy. The patient underwent secondary cytoreductive surgery for recurrent lesions, with postoperative recovery achieved. Further chemotherapy will be administered based on clinical condition and treatment response.
Authors: Phuong Pham Cam, Khoa Mai Trong, Thai Pham Van, Hung Nguyen Thanh, Khiem Nguyen Thanh, Khuy Doan Minh, Huyen Tong Thi, Lanh Pham Minh, Ngan Tran Thi Thuy, Ha Le Thanh
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4414451621
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