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Right ventricular injury during VV-ECMO for severe ARDS: Does time matter?

Year: 2025

Type: article

Abstract: Right ventricular injury (RVI) is a frequent complication during veno-venous extracorporeal membrane oxygenation (VV-ECMO) for severe respiratory failure. In this single-centre retrospective cohort of 40 patients, RVI was observed in 63%, being associated with increased ICU mortality. RVI at admission was more common in younger patients and those with shorter intubation periods pre-cannulation. RVI developing during VV-ECMO was associated with longer ECMO support, ICU stay, and a trend towards higher mortality. The timing of RVI likely reflects different pathophysiology, having different clinical implications. Improved monitoring of right ventricular function during VV-ECMO may enable earlier detection and intervention, potentially improving outcomes.

Source: Journal of the Intensive Care Society

DOI: 10.1177/17511437251374821

Authors: Robert McDonald, Jo-Anne Fowles, Robert Gatherer, Francisca Caetano

Institutions: University of Cambridge, Papworth Hospital NHS Foundation Trust

Language: English

Topic: Mechanical Circulatory Support Devices

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,900