Work

Clinical improvement of neuroretinitis over six-month follow-up period in an adult patient: a case report

Year: 2025

Type: article

Abstract: Background. Neuroretinitis is inflammation of the anterior optic nerve and peripapillary retina, presenting with vision loss, optic disc swelling, and a macular star. We report a case of neuroretinitis, the management provided, and the visual outcome. Case report. A 24-year-old man presented with a two-week history of blurry vision and fever. He lived with an unvaccinated cat. Examination revealed visual acuity of counting fingers at 2 meters in the left eye, optic disc swelling, a macular star, and a cecocentral scotoma. Laboratory tests were positive for IgG antibodies to cytomegalovirus (CMV) and rubella, indicating prior exposure. While CMV and rubella were considered possible causes, no definitive etiology was established. Treatment with high-dose corticosteroids led to gradual improvement in visual acuity, reaching 5/5 in both eyes, with resolution of the macular star over six months. A diagnosis of neuroretinitis, likely post-viral in origin, was made. Conclusions. Neuroretinitis is often triggered by infectious or post-viral autoimmune mechanisms. Treatment with methylprednisolone can result in significant clinical improvement.

Source: Romanian Journal of Neurology

DOI: 10.37897/rjn.2025.3.9

Authors: Rusydiana, Lukisiari Agustini

Institution: Universitas Airlangga

Language: English

Topic: Ocular Diseases and Behçet’s Syndrome

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Universitas Airlangga