Year: 2025
Type: article
Study design: Case Report
Abstract: Mastocystosis is a multisystem disorder characterized by mast cell deposition throughout internal organs. It can present in a similar fashion to anaphylaxis, with widespread mast cell degranulation triggered by a range of drugs, sleep deprivation, foods, and physical or emotional stress, such as pain or infection. We present a case of a woman in her 20s with her second pregnancy with suspected mastocytosis who required an elective cesarean section, and consider the implications of anesthetic management. A "recipe" with rationale has been devised to aid others who may come across a similar case in both the elective and emergency settings.
Source: Cureus
DOI: 10.7759/cureus.92864
Authors: William Phipps, Lydia Richardson, Erica Jolly
Institution: Southampton General Hospital
Language: English
Topic: Mast cells and histamine
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4414454102