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Long-Term Survival in Lung Cancer with Brain Metastases and Coronary Artery Stenosis: A Case Report

Year: 2025

Type: article

Abstract: Lung cancer is among the most diagnosed cancers worldwide, and its co-occurrence with coronary heart disease is life-threatening. Osimertinib is the standard treatment for epidermal growth factor receptor (EGFR) mutations in advanced non-small cell lung cancer (NSCLC). The addition of pemetrexed and carboplatin increases not only the efficacy but also the cardiotoxicity risk. We report a 59-year-old woman with NSCLC alongside brain, liver, and spleen metastases, who developed cardiovascular events following cancer therapy. With advanced imaging and multidisciplinary intervention, remarkable remission was achieved over two years. Reporting this case contributes to the understanding of its presentation and diagnostic challenges.

Source: Journal of the Saudi Heart Association

DOI: 10.37616/2212-5043.1452

Authors: Raghad O. Alharbi, Shahad J. AlShammary, Nasser E. Alotaibi, Ruba M. Aljohani, Bader A. Alotaibi, Ihab F. Suliman

Institutions: King Saud bin Abdulaziz University for Health Sciences, Princess Nourah bint Abdulrahman University, Prince Sattam Bin Abdulaziz University, Taibah University, National Guard Health Affairs

Language: English

Topic: Lung Cancer Treatments and Mutations

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4414458548

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