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Promising methods of treatment of the syndrome of senile fragility: focus on mesenchymal stem cells

Year: 2025

Type: article

Abstract: ABSTRACT. Senile frailty syndrome (SFS) develops in the elderly and senile as a result of aging-related degeneration and manifests itself in decreased psychological, physiological, and social functioning. Despite decades of research that have led to a growing understanding of the biological changes in SFS, there is currently no approved medical strategy that can effectively attenuate or reverse senile frailty. Mesenchymal stem cell (MSC) therapy is one of the promising methods of treating SFS. The presented review analyzes the capabilities of MSCs in the treatment of the SFS and its complications. It has been shown that the high clinical effectiveness and safety of the use of MSCs has been confirmed in the treatment of many diseases and pathological conditions, especially in elderly people with SFS.

Source: Infusion & Chemotherapy

DOI: 10.32902/2663-0338-8-2025-3-44-48

Author: O.A. Halushko

Institutions: D. F. Chebotarev State Institute of Gerontology of the National Academy of Medical Sciences of Ukraine, National Academy of Medical Sciences of Ukraine

Language: English

Topic: Mesenchymal stem cell research

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4414459444

FWCI:

Cites: 39

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