PRT3789 Is a First-in-Human SMARCA2-Selective Degrader That Induces Synthetic Lethality in SMARCA4 -Mutated Cancers
Year: 2025
Type: article
Source: Cancer Research
Authors: Michael Hulse, Min Wang, Chaoyi Xu, Jack Carter, Anjana Agarwal, Liang Lu, Philip Pitis, Neha Bhagwat, Joseph Rager, Justin Kurian, Corey Basch, Monisha Sivakumar, Jessica Burtell, Arpita Mondal, Alexander Grego, Andrew Moore, Carly Bachner, Komali Vykuntam, Anthony Reichelderfer, Jimin Park, Joy Cote, Miles Cowart, Olusola Peace Osinubi, Ludovic Bigot, Alice Da Silva, Catline Nobre, Melissandre Meteau, Miguel Soares, Hsin-Yao Tang, Klare Bersch, Chaofeng Dai, Ganfeng Cao, Bo Shen, Tom Emm, Stefan Ruepp, Jennifer Xavier, Chris Tankersley, Diane Heiser, Sang Hyun Lee, Sandy Geeganage, Bruce Ruggeri, Hong Lin, William Novotny, Jane Huang, Kris Vaddi, Andrew Combs, Peggy Scherle, Koichi Ito
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: closed
OpenAlex ID: W4414465618