Work

Development and evaluation of dandelion (Taraxacum officinale) leaves nanogel for the treatment of bacterial skin infection

Year: 2025

Type: article

Abstract: This study explores the antibacterial and pharmaceutical potential of Taraxacum officinale (dandelion) leaves, focusing on the development of a nanogel formulation for the treatment of bacterial skin infections. Leaves from dandelions were shade dried, powdered, then extracted using methanol, ethanol, and water through Soxhlet extraction. Flavonoids, alkaloids, tannins, saponins, and phenolic compounds were present as confirmed by the phytochemical screening. Solubility, partition coefficient and entrapment efficiency studies were performed to characterize the extract. The methanolic and ethanolic extracts exhibited excellent antibacterial activity against Staphylococcus aureus, having inhibition zones ranging between 12 - 20 mm and a MIC value was between 0.25 to 1.0 mg/mL. The findings suggest that dandelion leaves possess strong antibacterial properties and, when formulated into nanogels, could serve as a safe and natural alternative for managing bacterial skin infections.

Source: International Journal of Pharmaceutical Research and Development

DOI: 10.33545/26646862.2025.v7.i2c.187

Authors: Dev Prakash Dahiya, Anchal Sankhyan, Bipasha ., Jyoti Thakur

Institution: Abhilashi University

Language: English

Topic: Essential Oils and Antimicrobial Activity

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4414472407