Year: 2025
Type: article
Abstract: Chlorhexidine (1:6-di-4’-chlorophenyldiguanidohexane) has been a widely used antiseptic since its introduction in 1954. Alongside alexidine, it belongs to the group of cationic bisbiguanides with a broad spectrum of activity. Due to its diverse applications—such as in skin and mucous membrane disinfection, with use in mouthwashes, wound antiseptics, or catheterization—chlorhexidine has been an integral part of healthcare and beyond as an antiseptic for decades. Despite its generally good tolerability, chlorhexidine is also a potent allergen that can trigger both type I and type IV hypersensitivity reactions. In the following article, we provide an overview of anaphylactic reactions caused by chlorhexidine.
Source: Allergo Journal International
Authors: Elias Marquart, Tamar Kinaciyan
Institution: Medical University of Vienna
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,390
Funder: Medizinische Universität Wien
OpenAlex ID: W4414473572