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A role for Fas/FasL-dependent NK-mediated cytotoxicity in infants with perinatal HIV

Year: 2025
Type: article
Abstract: transcript expression, suggesting that impaired Fas/FasL signaling may limit effective early immune control. These results highlight a potentially underappreciated role for Fas/FasL in shaping antiviral immunity in pediatric HIV.
Source: iScience
DOI: 10.1016/j.isci.2025.113637
Authors: Akshay Iyer, Lesley de Armas, Vinh Dinh, Suresh Pallikkuth, Rajendra N. Pahwa, Paula Vaz, Maria Grazia Lain, Savita G. Pahwa
Language: English
Subfield: Virology
Open Access status: gold
Estimated APC paid: $3,240
Funders: Styrelsen för Internationellt Utvecklingssamarbete, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, University of Miami, Johns Hopkins University, Sylvester Comprehensive Cancer Center, University of Miami Health Systems, National Institutes of Health, Miami Center for AIDS Research, Center for AIDS Research, University of Washington, Leonard M. Miller School of Medicine, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Institute on Drug Abuse, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, Fogarty International Center, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Child Health and Human Development, Office of AIDS Research
Awards: G1046110846, G1244280259, G169756849, G1988405744, G2630461588, G3138949240, G4044828089, G5431849782, G666104176, G6704699822, G7291307179, G797497145, G8968883607, G9000010714, G9000016026, G9000016284, G9000028848, G9000058877, G9000299978
OpenAlex ID: W4414477349
FWCI: 0.453
Cites: 55
Cited by: 1
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