Clinical value of 99mTc-MIBI scintigraphy combined with posttherapeutic 131I whole-body scanning in patients with differentiated thyroid cancer with sTg ≥10 ng/mL before initial radioiodine therapy: a retrospective study
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: I WBS) in patients with DTC and sTg ≥10 ng/mL before initial radioactive iodine therapy (RAIT). Additionally, we analyzed the differences in the therapeutic efficacy of RAIT among different groups. Methods: I WBS negative. The response to RAIT was classified as excellent response (ER), indeterminate response (IDR), biochemical incomplete response (BIR), and structural incomplete response (SIR) according to the 2015 ATA guidelines. The efficacy of RAIT in different groups was further analyzed. Results: I WBS had similar diagnostic efficacy (all P values >0.05). The difference in response to RAIT between group 4 and group 2 (P<0.001) and between group 4 and group 1 (P<0.001) was significant. However, in terms of distant metastasis and local metastasis, the only significant difference was between group 1 and group 4 (F=6.925; P=0.015). Conclusions: I WBS in patients with DTC with bone metastasis. It may lead to the early detection of bone metastasis before RAIT and guide clinical management.
Institution: Affiliated Hospital of Qingdao University
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4414483629