Charge modulation in D–A–D molecules: an acid-responsive NIR-II nanoplatform for imaging and photothermal therapy
Year: 2025
Type: article
Abstract: experiments demonstrated that SMIC-10004 NPs enabled high-resolution and long-term NIR-II imaging, and the nanoparticles significantly inhibited tumor growth under laser irradiation, showing superior photothermal therapeutic efficacy with good biocompatibility. Overall, this study not only provides valuable guidance for the rational design of charged D-A-D dyes, but also presents a promising platform for NIR-II-based theranostic applications.
Source: Biomaterials Science
DOI: 10.1039/d5bm01084e
Authors: Shu Gao, Jiahui Wang, Xiaonan Wei, Jun Wang, Yuanpeng Jiang, Boyu Tan, Yeshan Qin, Xiaoyang Zhu, Ruihu Song, Chunrong Qu, Kun Qian, Zhen Cheng
Institutions: Chinese Academy of Sciences, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, State Key Laboratory of Drug Research, Tianjin University of Traditional Chinese Medicine, Shandong First Medical University, ShanghaiTech University, Nanjing University of Chinese Medicine
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: hybrid
Awards: G3843351077, G4542992752, G605575275
OpenAlex ID: W4414485195