Work

Systemic and regional hemodynamic and (de)oxygenation responses across repeated breath-holds

Year: 2025

Type: article

Abstract: In nondivers, regional cerebral (de)oxygenation responses varied greatly across repeated breath-holds, whereas peripheral tissue responses were comparable. At IBM onset, cerebral oxygenation increased significantly during the first breath-hold but showed progressively smaller changes in subsequent attempts. In the periphery, a triphasic (de)oxygenation pattern was identified. Its final phase-characterized by a further oxygenation decline-coincided with increased cerebral oxygenation, supporting the concept of sympathetically mediated vasoconstriction and selective blood redistribution toward vital organs.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00508.2025

Authors: Antonis Elia, Mikael Gennser, Ola Eiken, Michail E. Keramidas

Institutions: Karolinska Institutet, Swedish Armed Forces, National and Kapodistrian University of Athens

Language: English

Topic: Cardiovascular and Diving-Related Complications

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Försvarsmakten