Work

ZJK-807: A Selective PROTAC Degrader of KRASG12D Overcoming Resistance in Pancreatic Cancer

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c01034

Authors: Zhaojuan Liu, Heping Zheng, Yanqing Tian, Zhuoyue Li, Sai Zhang, Siqi Zhang, Shumin Ma, Xiao Wang, Chong Qin

Institutions: Ocean University of China, Marine Biomedical Research Institute of Qingdao, Qingdao National Laboratory for Marine Science and Technology

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: Key Technology Research and Development Program of Shandong

Award: G2179247509

OpenAlex ID: W4414495393

FWCI: 2.611

Cites: 38

Cited by: 10

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