Work

Abstract B015: CDK12 pharmacological targeting promotes cell death by abrogating DNA damage response, impairs PAX3-FOXO1 expression and synergizes with BRD4 and PARP inhibitors in fusion positive rhabdomyosarcoma

Year: 2025

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.pediatric25-b015

Authors: Marika Attili, Lucrezia D'Archivio, Riccardo Mazzocchi, Francesca Antonella Aiello, Matteo Cassandri, Silvia Pomella, Adam D. Durbin, Francesco Marampon, Kim PJ Schellekens, Michael T Meister, Jarno Drost, Concetta Quintarelli, Simone Sidoli, Michele Ceribelli, Craig J Thomas, Franco Locatelli, Biagio De Angelis, Kristy R Stengel, Rossella Rota

Institutions: Bambino Gesù Children's Hospital, St. Jude Children's Research Hospital, Sapienza University of Rome, Princess Máxima Center, Albert Einstein College of Medicine, National Institutes of Health, National Center for Advancing Translational Sciences

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4414501250

Cites:

Cited by:

Related to: