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Role of Molecular Analysis in Thyroid Malignancy:advances,challenges and Clinical Implications

Year: 2025

Type: article

Abstract: Thyroid malignancies are the most common endocrine cancers, accounting for nearly 3–5% of all newly diagnosed cancers globally, with a steadily rising incidence over the past three decades (Lim et al., 2021). Papillary thyroid carcinoma (PTC) represents approximately 80–85% of all thyroid cancers, followed by follicular, medullary, and anaplastic subtypes (Cabanillas et al., 2019). Although mortality remains relatively low compared to other solid tumors, advanced and aggressive variants such as anaplastic thyroid carcinoma are associated with poor survival outcomes (Matos et al., 2020). The growing prevalence has made thyroid malignancy a significant public health concern, necessitating improved diagnostic and therapeutic strategies (Kitahara & Sosa, 2020).

Source: Journal of Carcinogenesis

DOI: 10.64149/j.carcinog.24.3.709-715

Authors: Shanmukh Kamath, Raghunath Shanbag, SHIBANI ANCHAN, AISHWARYA HEGDE

Institution: Shri Dharmasthala Manjunatheshwara University

Language: English

Topic: Thyroid Cancer Diagnosis and Treatment

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,500