A 3 -Mannich coupling reaction via chiral propargylglycine Ni( ii ) complex: an approach for synthesizing enantiomerically enriched unnatural α-amino acids
Year: 2025
Type: article
Abstract: and experimental evaluations for reliable biological profiling. The presented strategy provides a versatile platform for the synthesis of structurally diverse, enantiomerically pure non-proteinogenic amino acids with promising bioactivity, offering valuable prospects for drug discovery and enzymatic inhibition studies.
Source: RSC Advances
DOI: 10.1039/d5ra04554a
Authors: Liana Hayriyan, Anna Grigoryan, Hasmik Gevorgyan, Avetis Tsaturyan, Armen Sargsyan, Peter Langer, Ashot Saghyan, Anna Mkrtchyan
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,042
Awards: G6900380059, G7788868505
OpenAlex ID: W4414518641