Terrestrial radiotherapy alters microhardness and surface micromorphology of dental restorative materials: an in vitro study
Year: 2025
Type: article
Abstract: Background Therapeutic radiotherapy, commonly used in the treatment of head and neck cancers, may alter the mechanical and surface properties of restorative dental materials. Understanding these changes is essential for ensuring the long-term success of restorations in oncology patients. Methods An in vitro study was conducted on 90 disc-shaped specimens (n = 30 each) of three restorative materials: 3M™ Filtek™ Bulk Fill, Charisma Topaz One, and Cention N. Samples were subjected to two radiation protocols: (i) 70 Gy in 35 fractions (2 Gy/day), and (ii) 45 Gy in 5 fractions (9 Gy/day). Vickers microhardness testing and scanning electron microscopy (SEM) were performed 48 h post-irradiation. Results Filtek™ Bulk Fill exhibited the highest pre-radiation hardness (83.1 ± 2.3 HV), followed by Charisma Topaz One (74.5 ± 2.8 HV) and Cention N (69.8 ± 2.1 HV). After exposure to 70 Gy, a statistically significant reduction in microhardness was observed across all materials (p < 0.05), with Bulk Fill remaining the least affected (74.3 ± 2.1 HV). SEM images confirmed surface degradation in all groups, with varying degrees of filler particle exposure. Conclusions Ionizing radiation alters both microhardness and surface morphology of restorative materials, with bulk-fill composites demonstrating greater resilience. These findings warrant further investigation in vivo to understand long-term clinical implications.
Source: Frontiers in Oral Health
Language: English
Subfield: Orthodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,077
OpenAlex ID: W4414520078