Work

Human papillomavirus: An update

Year: 2025

Type: article

Abstract: Human papillomaviruses (HPV) comprise a group of DNA viruses with more than 450 types identified. HPV represents one of the most common viral infections globally. HPV can cause a wide spectrum of clinical disease depending on type, including benign lesions (cutaneous or anogenital warts), premalignant lesions (intraepithelial neoplasia), and anogenital cancers; however, infection may also frequently remain subclinical. Even though the role of HPV in the pathogenesis of penile, vulval, and anal intraepithelial neoplasia and other cutaneous diseases has been recognized, robust evidence for the role of screening and effective management is often lacking. The implementation of prophylactic vaccination for young people and at-risk adults in high-income countries has proven successful, and now there is growing interest in postexposure vaccination.

Source: Clinics in Dermatology

DOI: 10.1016/j.clindermatol.2025.09.012

Authors: Manik Kohli, Christopher B. Bunker, Georgios Kravvas

Institutions: Central and North West London NHS Foundation Trust, University College London, University College Hospital, University College London Hospitals NHS Foundation Trust

Language: English

Topic: Cervical Cancer and HPV Research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,760