Work

Lipid nanomedicine simultaneously inhibits BRD4/PI3K and MDM2/XIAP signaling pathways for effective treatment of Medulloblastoma

Year: 2025

Type: article

Source: Journal of Controlled Release

DOI: 10.1016/j.jconrel.2025.114266

Authors: Bharti Sethi, Aditya Gupta, Qiaoyu Pan, Sohan Mahto, Ajaykumar Chittipolu, Helen Erickson, Virender Kumar, Yanfei Chen, Zhongzhi Wu, Yuxiang Dong, Wei Li, Donald R. Ronning, Donald W. Coulter, Ram I. Mahato

Institutions: University of Nebraska Medical Center, University of Tennessee Health Science Center

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Children's Hospital of Philadelphia, University of Nebraska Medical Center, Nebraska Department of Health and Human Services, National Institutes of Health, National Cancer Institute, National Institute of Neurological Disorders and Stroke

Awards: G4746333605, G6070080256, G6354616342, G6899411537, G7676060446, Dual inhibition of MDM2 and XIAP as a therapeutic strategy in cancer, G9000125045, G9000265850, G96429297

OpenAlex ID: W4414522773

FWCI: 0.184

Cites: 28

Cited by: 1

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