Work

Regioselective terminal bromination of fluorinated oligophenylenes

Year: 2025

Type: article

Abstract: Herein, we demonstrate an unprecedentedly selective terminal bromination of fluorinated biphenylenes and oligophenylenes in the presence of excess metallic iron. The reaction can be carried out under ambient conditions at room temperature, yielding the target compounds with up to 98% yield. The high regioselectivity and scalability make this approach superior to existing methods.

Source: Chemical Communications

DOI: 10.1039/d5cc05074j

Authors: Nour-Eddine El Alaoui, Konstantin Y. Amsharov

Institution: Martin Luther University Halle-Wittenberg

Language: English

Topic: Synthesis and Properties of Aromatic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funder: Deutsche Forschungsgemeinschaft

Award: G5533406556