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Lupus Nephritis Developed in Patient postchemotherapy for Gestational Trophoblastic Neoplasia

Year: 2025

Type: article

Abstract: The association of GTN with kidney diseases is infrequent, with scarce published case reports. This case report describes the development of lupus nephritis in a 30-year-old female following chemotherapy for high-risk gestational trophoblastic neoplasia (GTN). Despite obtaining remission from GTN, the patient presented with persistent anemia, neutropenia, and renal dysfunction, directing to additional investigation. The diagnosis of lupus nephritis was confirmed through serological tests, renal biopsy, and the identification of specific autoimmune markers. This case promotes the importance of considering autoimmune diseases, comprising lupus nephritis, in the differential diagnosis of patients with hematologic anomalies after finishing her chemotherapy for GTN.

Source: Biomedical Journal of Scientific & Technical Research

DOI: 10.26717/bjstr.2025.63.009866

Authors: Aref Zribi, Asma Atfeesh, Marwa Al Riyami

Institutions: Sultan Qaboos Comprehensive Cancer Care & Research Center, Sultan Qaboos University Hospital

Language: English

Topic: Systemic Lupus Erythematosus Research

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4414530984