Work

Pacing-Induced Cardiomyopathy in a Transplanted Heart Treated With Left Bundle Branch Pacing

Year: 2025

Type: article

Abstract: BACKGROUND: Atrioventricular (AV) block is a potential complication of orthotropic heart transplantation (OHT). The optimal cardiac pacing method is largely unexplored in patients after OHT. CASE SUMMARY: We present a patient with AV block after OHT in whom right ventricular pacing resulted in pacing-induced cardiomyopathy (PICM). Left ventricular function was restored with left bundle branch pacing. DISCUSSION: AV block is an uncommon complication after OHT that requires ventricular pacing. Ventricular dyssynchrony induced by right ventricular pacing may be associated with increased risk for PICM in OHT recipients. Cardiac physiologic pacing should be considered as the primary pacing strategy in this population. TAKE-HOME MESSAGES: OHT recipients may be at increased risk for PICM. Left bundle branch pacing is an effective strategy for both prevention and treatment of PICM.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2025.105537

Authors: Nicholas Tomassoni, Roy Sun, Marc Erickson, Pugazhendhi Vijayaraman

Institutions: Geisinger College of Health Sciences, Geisinger Wyoming Valley Medical Center

Language: English

Topic: Cardiac pacing and defibrillation studies

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $850