Work

A bridging thiocarbyne ligand in diiron( i ) complexes enables unconventional isomerization pathways and structural diversity leading to potent cytotoxicity

Year: 2025

Type: article

Abstract: Diiron bis-cyclopentadienyl complexes of type [Fe 2 Cp 2 (L′)(L)(μ-CO)(μ-CSMe)] + can be designed by appropriate choice of the monodentate ligands (L, L′) to tune aqueous solubility, lipophilicity, isomerization processes and cancer cell cytotoxicity.

Source: Inorganic Chemistry Frontiers

DOI: 10.1039/d5qi01498k

Authors: Lorenzo Biancalana, Ekatarina Mihajlović, Gianluca Ciancaleoni, Marija Mojić, Sanja Jelača, Stefano Zacchini, Guido Pampaloni, Biljana Dojčinović, Danijela Maksimović-Ivanić, Sanja Mijatović, Fabio Marchetti

Institutions: University of Pisa, University of Belgrade, Institute for Biological Research “Siniša Stanković”, University of Bologna, Institute of Chemistry, Technology and Metallurgy

Language: English

Topic: Organometallic Complex Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja, Università di Pisa

Awards: G1820281366, G2398874744

OpenAlex ID: W4414542256

FWCI:

Cites: 100

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