Year: 2025
Type: article
Abstract: The expression of molecular dissymmetry in crystal form has been studied since Pasteur correlated macroscopic and microscopic chirality by measuring the optical activity of solutions of enantiomorphous tartrate salt crystals. Here, we show a direct correlation between enantiomorphous metal-organic framework (MOF) crystals and the chirality of the molecular structure. The geometry of the habits is correlated with single-crystal optical activity along the accessible low-symmetry directions. Weak X-ray scattering from small crystals was consistent with a hexagonal, enantiomorphous space group. However, the heterochirality of the mirror image forms could not be established with X-rays, necessitating a different approach. The optical circular birefringence of the enantiomorphs as evidenced by chiroptical imaging with a complete polarimetric microscope, was used to correlate optical and morphological chirality.
Source: Nature Communications
Institutions: Weizmann Institute of Science, New York University
Language: English
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $6,990
Awards: Patterning Mesoscale Chirality by Guided Crystal Twisting, G1472743852, Multi-Stimuli Responsive Molecular Systems and Materials, Collaborative Research: Charge Transport in Helicoidal Molecular Crystals, G434337789, G61249596, NYU Materials Research Science and Engineering Center, G6674151550, G821361635
OpenAlex ID: W4414556692