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Transdermal Drug Delivery Systems: A Focused Review of Physical Methods of Permeation Enhancement

Year: 2025

Type: article

Abstract: The skin is the largest organ of the body and has been widely utilized as a route of drug delivery. Transdermal drug delivery systems (TDDS) offer numerous advantages over conventional routes such as bypassing hepatic first-pass metabolism, achieving controlled plasma levels, and improving patient compliance. This paper reviews the physical methods of permeation enhancement including iontophoresis, ultrasound, microneedles, and other device-assisted strategies. Schematic illustrations are included for better understanding.

Source: International Journal For Multidisciplinary Research

DOI: 10.36948/ijfmr.2025.v07i05.55640

Authors: Falgunee Ghadi, Alfiya Rehmani, Divyata Chavan, Fatma Khan, Krutika Bhoir

Language: English

Topic: Advancements in Transdermal Drug Delivery

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4414559159

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