Work

Synthetic autotrophic yeast enables high itaconic acid production from CO 2 via integrated pathway and process design

Year: 2025

Type: article

Abstract: We show that combining pathway and process engineering enables synthetic autotrophic K. phaffii to produce ∼12 g L −1 itaconic acid from CO 2 , highlighting the role of interplay between native and heterologous metabolic pathways and process design.

Source: Green Chemistry

DOI: 10.1039/d5gc03149d

Authors: Özge Ata, Lisa Lutz, Michael Baumschabl, Diethard Mattanovich

Institutions: Austrian Centre of Industrial Biotechnology (Austria), BOKU University

Language: English

Topic: Microbial Metabolic Engineering and Bioproduction

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDGs: Responsible consumption and production, Climate action

Open Access status: hybrid