Investigation of Factors Affecting Histopathological Upgrade in Breast Papillary Lesions: A Single-Center Study
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Breast papillary lesions are uncommon but clinically important due to their potential for histological upgrade. This study aimed to determine the factors that may influence histopathological upgrade in breast papillary lesions. Methods: < 0.05). Associations were investigated between histopathological shift and variables including age, menopausal status, comorbidities, family history, palpable mass, symptom type, lesion laterality and quadrant, Breast Imaging Reporting and Data System (BI-RADS) category, microcalcification, breast density, echogenicity, lesion structure, contour, and biopsy method. Results: > 0.05). Conclusions: In breast papillary lesions, menopause, certain comorbidities, and specific radiological factors (such as BI-RADS category and calcifications) may increase the risk of histopathological transition. These findings underscore the importance of a multidisciplinary approach in diagnosing and managing intraductal papillomas. Larger scale studies could further refine risk stratification, potentially reducing unnecessary surgeries while facilitating earlier identification of high-risk patients.
Source: Breast Care
DOI: 10.1159/000548105
Institution: Erciyes University
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4414566187