Year: 2025
Type: article
Study design: Case Report
Abstract: Systemic lupus erythematosus (SLE) is a connective tissue disorder with an unknown cause that primarily impacts women of reproductive age. We present a case of a new-onset elderly male SLE with positive anti-nuclear antibodies (ANAs) and clinical presentations including hemoptysis, fatigue, weight loss, multiple skin and mucosal lesions, and intractable pyrexia. The European League Against Rheumatism guidelines and comprehensive evaluations were used to establish a diagnosis of SLE. The prevalence of SLE in males is lower compared to women, often presenting with negative ANA, which makes diagnosis challenging. An unusual and striking feature in this case was hemoptysis as the initial presenting symptom, a rare manifestation that highlights the need for heightened suspicion. Thus, having a high degree of suspicion as a primary care doctor helps in early diagnosis, improves treatment outcomes, and leads to a better quality of life.
Source: Cureus
DOI: 10.7759/cureus.93360
Authors: Tamanna Mohta, Chukwuemeka Umeh, Anushka Chokshi
Institution: St. Mary Medical Center
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4414567267