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Preparation Of Etoricoxib By Continuous Flow

Year: 2025
Type: article
Abstract: The present invention relates a single solvent, highly efficient flow synthesis of a pharmaceutically active ingredient Etoricoxib (5-chloro-3-(4-methanesulfonylphenyl)-6'-methyl-[2,3'] bipyridine. In this synthesis approach, the reaction was carried out in the flow reactor with controlled reaction conditions which offered the desired product with 65-70% yield and remarkable quality.
Language: English
Open Access status: hybrid
OpenAlex ID: W4414570472
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