Certainly! Apologies for the previous omissions. Below is the complete LaTeX document that includes all the requested sections, arguments, code snippets, and proofs, organized logically into a single cohesive document. “‘latex N-Directed, Co-Catalyzed Functionalization of Distal C(sp3)−H Bonds with Phenols: Arylation vs. Aryloxylation
Year: 2025
Type: preprint
Abstract: Chemo- and regioselective functionalization of free phenols is a continuing challenge. Herein, cobalt-catalyzed cross-dehydrogenative coupling (CDC) of phenols with distal C(sp 3 )−H bonds is achieved. The reaction exhibits good to excellent chemo- and regioselectivity, delivering ortho -alkylated phenols and alkyl aryl ethers respectively. The reaction could involve a radical process and the presence of Na 2 CO 3 or DBU in combination with Co catalyst is essential for the chemo- and regioselectivity.
Authors: Yu-Han Wang, Hai-Tao Qin, Feng Liu
Institution: Soochow University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
OpenAlex ID: W4414577142
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