Assessment of healthcare-associated infection of Klebsiella pneumoniae isolated from patients attended private clinics in Basrah governorate
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Occurrence of Klebsiella pneumoniae in patients who attended private clinics poses a threat to increase antibiotics resistance and sporadic transmission, it has acquired a significance similar to that of infections in hospitals and other healthcare facilities. Aim: to highlight Klebsiella pneumoniae, its antibiotics susceptibility pattern, type of resistance, prevalence and frequency in private medical clinics. Methods: 180 clinical samples obtained from urine, blood, sputum, and surgical wounds that subjected to identification and susceptibility analysis by biochemical means, VITEK® 2 and PCR for gene identification. Results: Out of 180 specimen,118 isolates of Klebsiella pneumoniae showed sensitivity to colistin and tigecycline, with high resistance to third-generation of cephalosporins and fluoroquinolones. (77.9%) of multidrug-resistant isolates exhibited production of extended spectrum beta-lactamases (ESBLs), (66%) exhibited carbapenemase activity. The antibiotic resistance genes blaCTX-M was the most commonly observed among other detected resistance genes. Conclusion: Based on the frequency of infection of patients attending private medical clinics with Klebsiella pneumoniae, attention must be paid to this pathogen demonstrates resistance to beta-lactams along with carbapenems and additional antibiotic groups.
Institution: University of Basrah
Language: English
Subfield: Molecular Medicine
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4414582294
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