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Descemet’s Membrane Detachment Following Inadvertent Intrastromal Injection of an Ophthalmic Viscoelastic Device

Year: 2025

Type: article

Abstract: Hypotony is a well-documented postoperative complication of glaucoma filtration surgery. Management may include the injection of an ophthalmic viscoelastic device (OVD) into the anterior chamber. This case report describes a 45-year-old woman with juvenile-onset open-angle glaucoma who developed clinical hypotony after trabeculectomy surgery augmented with mitomycin-C. An intracameral injection of Healon5® (Johnson & Johnson Vision, USA) was attempted to restore physiological intraocular pressure (IOP); however, Healon5® was inadvertently introduced into the corneal stroma, causing a localised Descemet's membrane detachment (DMD). Following non-resolution with observation and attempted surgical evacuation, an intracameral air tamponade successfully addressed the DMD. An intracameral air tamponade may provide a quicker alternative to prolonged observation, particularly for highly cohesive OVDs such as Healon5®.

Source: Cureus

DOI: 10.7759/cureus.93383

Authors: Adam Bharmal, Shankar Ramanathan, Balasubramanian Ilango, Abhijit A Mohite

Institution: The Royal Wolverhampton NHS Trust

Language: English

Topic: Corneal surgery and disorders

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4414584656