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Septic Arthritis Caused by Klebsiella pneumoniae in a Patient with B-cell Acute Lymphoblastic Leukemia: A Case Report

Year: 2025

Type: article

Abstract: This case report describes a 53-year-old female with newly diagnosed B-cell acute lymphoblastic leukemia (ALL) who developed septic arthritis due to Klebsiella pneumoniae during induction chemotherapy with a modified CALGB protocol.The diagnosis was challenging, requiring multiple imaging modalities (ultrasound, MRI, and PET scan), and was ultimately confirmed via synovial fluid culture obtained through arthroscopy.Despite targeted antibiotic therapy and surgical intervention, the patient experienced persistent joint dysfunction, necessitating referral for total hip arthroplasty.This case highlights the importance of high clinical suspicion for septic arthritis in immunocompromised patients, the critical role of synovial fluid analysis in diagnosis, and the need for multidisciplinary management.

Source: Journal of Advances in Medical and Biomedical Research

DOI: 10.30699/jambr.33.158.237

Authors: Nasrin Gholami, Shalaleh Aghaei, Gholamreza Ravaei, Shahab Mahdipour

Institution: Tabriz University of Medical Sciences

Language: English

Topic: Orthopedic Infections and Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Tabriz University of Medical Sciences, University of Tabriz