Work

Objective assessment of cardiac function using patient-specific biophysical modeling based on cardiovascular MRI combined with catheterization

Year: 2025

Type: article

Abstract: Combining cardiovascular MRI and catheterization data into a single framework provides important quantities of cardiovascular physiology. However, multimodality data are often subjected to measurement errors (e.g., time-dyssynchrony between volume and pressure signals) limiting their clinical interpretation. This study demonstrates that coupling clinical data with biomechanical modeling is an efficient way to filter measurement noise (providing, e.g., high-quality pressure-volume loops) and derive meaningful quantities of cardiovascular physiology.

Source: American Journal of Physiology-Heart and Circulatory Physiology

DOI: 10.1152/ajpheart.00232.2025

Authors: Maria Gusseva, Daniel A. Castellanos, Surendranath Veeram Reddy, Tarique Hussain, Dominique Chapelle, Radomír Chabiniok