Çölyak hastalarında non-alkolik yağlı karaciğer hastalığı yaygınlığı artmıyor: Kesitsel çalışma
Year: 2024
Type: article
Study design: Observational Study
Abstract: Objective: Celiac disease (CD) is associated with liver diseases and could be associated Non-alcoholic fatty liver disease (NAFLD) due both diseases have same etiopathogenetic risk factors such as altered gut microbiota and intestinal permeability. Despite this tight association of these disease, there are few studies on this subject. Therefore, we aimed to determine the prevalence of NAFLD in patients with celiac disease.Material and Methods: This cross sectional, was carried out in a tertiary health center. The aim of the study is to determine the frequency of NAFLD in CD patients treated with a gluten-free diet (GFD) for at least 6 months. The secondary aim was to assess the relative risk of NAFLD in CD patients treated with a GFD for at least 6 months. Patients with diagnosed CD and a GFD was initiated at least 6 months before were included the study as a group A. The control group (group B) was selected from the outpatients who applied to our polyclinic with dyspepsia. Hepatosteatosis was diagnosed by ultrasonographic examination.Results: Group A and Group B were similar in terms of age, gender frequency, body mass index (BMI) and presence of diabetes mellitus. The frequency of NAFLD was 22.7% in Group A and 28.1 in Group B (P = 0.35). Advanced age, high BMI, high blood sugar, presence of DM was a risk factor for NAFLD.Conclusion: Individuals with celiac disease are not at increased risk of nonalcoholic fatty liver disease compared to the general population.
Source: DergiPark (Istanbul University)
Institutions: Tokat Gaziosmanpaşa Üniversitesi, Samsun University
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4414587756