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A practical synthesis of enantiopure syn -β-amino-α-hydroxy acids from α-amino acids with application in the formal syntheses of l -TFB-TBOA and (S)-vigabatrin

Year: 2025

Type: article

Abstract: a cleaner process relative to the conventional one-pot oxidation. The practical value of this transformation has been demonstrated in the formal synthesis of l-TFB-TBOA and (S)-vigabatrin.

Source: RSC Advances

DOI: 10.1039/d5ra05586e

Authors: Bohua Long, Peng Zhang, Mengmeng Jiang, Pengfei Guo, Xuanluan Chen, Shunlei Shang, Zhengzhi Wu

Institutions: Shenzhen University, Shenzhen Second People's Hospital, China-Japan Friendship Hospital

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,042

Funder: Natural Science Foundation of Shenzhen City

Award: G859707293

OpenAlex ID: W4414625643

FWCI:

Cites: 33

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