Prevalence of uncomplicated erosive and ulcerative lesions of the upper gastrointestinal tract in patients of a surgical hospital
Year: 2025
Type: article
Study designs: Systematic Review, Meta-Analysis
Abstract: INTRODUCTION: In the last decade, patients with various surgical pathologies have been demonstrating an increase in uncomplicated erosive and ulcerative lesions (EULs) of the proximal part of the gastrointestinal tract (GIT). Knowledge of the current prevalence of this pathology has both scientific and practical significance. AIM: Assessment of the prevalence of uncomplicated EULs in the upper GIT in a multidisciplinary surgical hospital and analysis of factors that determine the structure of the identified prevalence. MATERIALS AND METHODS: Meta-analysis of 20 clinical studies from eLibrary, PubMed databases from 2010 to 2023 devoted to uncomplicated EULs of GIT, stomach and duodenum. RESULTS: Based on the examination of 4,337 patients (data of domestic literature sources) and 13,024,812 (data of foreign sources), the prevalence of acute erosive and EULs of the upper GIT ranged from 7.4 to 100% and from 1.7 до 100% respectively. High heterogeneity of samples confirms a wide variation of the incidence of the analyzed kind of lesion both in our country and abroad determined by the influence of various factors, specific to both each patient and the profile of a surgical hospital. CONCLUSION: The meta-analysis demonstrates a high range of incidence of uncomplicated acute EULs of the proximal GIT, which requires further clarification of the true prevalence of the pathology under study and of other causes that influence the development of destructive pathological alterations.
Authors: Lyudmila A. Ushaeva, Dmitry V. Zavyalov, Leonid B. Shubin, Ilya N. Staroverov, Yuri V. Chervyakov, Sergey N. Pamputis
Institution: Yaroslavl State Medical Academy
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4414628561