Work

Not Your Usual Culprit: Relapsing Salmonella enterica Serovar Infantis Urinary Tract Infection

Year: 2025

Type: article

Abstract: serovar Infantis (S. Infantis) is exceptionally rare and typically linked to host vulnerabilities. We report a case of a woman in her 60s with metastatic renal cancer, diabetes, chronic kidney disease, and prior splenectomy who developed three episodes of UTI within a year. Repeated urine cultures grew S. Infantis, and whole-genome sequencing confirmed relapse from intestinal colonization. After sequential short antibiotic courses, sustained resolution followed a seven-day regimen combined with reinforced pet-related hygiene measures. This case highlights the importance of considering unusual uropathogens, using genomic tools to confirm persistence, and addressing potential zoonotic reservoirs.

Source: Cureus

DOI: 10.7759/cureus.93577

Authors: Tania Islam, Darshana Wickramasinghe, Usman Ul Haq, KH Imranul Alam

Institution: Medway NHS Foundation Trust

Language: English

Topic: Salmonella and Campylobacter epidemiology

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4414630527