Integrative physiological study of radiation-induced lung injury: effects on cardiac function and kidney integrity
Year: 2025
Type: article
Abstract: Radiotherapy is used to treat chest tumors, but may induce radiation-induced lung injury (RILI) in some patients. In the current RILI model, significant changes were observed in both irradiated and nonirradiated lungs. Increased right ventricle afterload and kidney morphological alterations were detected, suggesting vascular congestion. This study highlights the well-known impact of RILI on lungs but also emphasizes the often-overlooked effects on heart and kidneys in clinical practice.
Source: Journal of Applied Physiology
Authors: Lucas Rodrigues de Moraes, Maicon Luiz de Lima, Antônio Pedro Abido Ribeiro, Nazareth de Novaes Rocha, Tula Celeste Wilmart Gonçalves, Rodrigo Jorge Vianna Barbosa, Klara de Souza Roque, Giovanna Costa Ferreira Santos, Amanda Pereira da Cruz, Rodrigo Gonzaga Veras, Sabrina Araújo Ferreira, Pedro Henrique Lima da Conceição, Raquel Ferreira de Magalhães Sacramento, Adriana Lopes da Silva Vilardo, Vera Luiza Capelozzi, Camila Machado Baldavira, Sarah Aparecida dos Santos Alves, Fernanda Ferreira Cruz, Patricia Rieken Macedo Rocco, Celso Caruso-Neves, Sergio Augusto Lopes de Souza, Lorenzo Ball, Pedro Leme Silva
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4414645037