Year: 2025
Type: article
Abstract: Mental disorders such as depression and anxiety are leading causes of disability. This review evaluates the potential of resistance training as an adjunctive therapy and its effect on symptoms. A synthesis of meta-analyses, systematic reviews, and randomized controlled trials indicates neurobiological benefits (enhanced brain plasticity and increased BDNF), hormonal effects (reduced cortisol), and anti-inflammatory effects (decreased TNF-α and IL-6). Resistance training also improves self-esteem, sleep quality, and social connectedness, increasing its applicability across patient populations. As a complement to pharmacotherapy and psychotherapy, it offers additional benefits and fewer barriers to implementation. Its program flexibility allows easy integration into personalized care and public-health strategies. Future research should standardize protocols, optimize intensity and duration, and assess long-term effects. Technologies — wearables and mobile apps — may improve adherence and accessibility. Resistance training has the potential to substantially enrich mental healthcare and improve quality of life for people with depression, anxiety, and other mental disorders.
Language: English
Topic: Physical Activity and Health
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $100
OpenAlex ID: W4414651656