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HBOT-induced noncardiogenic pulmonary edema in acute carbon monoxide poisoning: A case report and mechanistic insights

Year: 2025

Type: article

Abstract: RATIONALE: Acute carbon monoxide poisoning is a common medical emergency, and hyperbaric oxygen therapy (HBOT) serves as the cornerstone of treatment. Although rare, serious complications such as acute pulmonary edema (APE) can be life-threatening. Most reported cases involve patients with preexisting cardiac conditions, making this case of APE in a patient without cardiac comorbidities particularly noteworthy. PATIENT CONCERNS: A 35-year-old male patient developed dyspnea accompanied by severe coughing during the decompression phase of HBOT for acute carbon monoxide poisoning. DIAGNOSES: Emergency chest computed tomography showed APE. INTERVENTIONS: Immediate endotracheal intubation and mechanical ventilation were initiated, along with a combination of diuretics, glucocorticoids, and bronchodilators. OUTCOMES: During the 3-month follow-up period, the patient remained asymptomatic with complete resolution of clinical manifestations. LESSONS: Although HBOT-induced APE is a rare complication, its critical clinical implications necessitate rigorous monitoring of respiratory dynamics and oxygenation status during treatment sessions.

Source: Medicine

DOI: 10.1097/md.0000000000044925

Authors: Min-Xue Yao, Yu-Yang Chen, Zhi-Jian Gu

Institutions: Jiangsu University, First People's Hospital of Kunshan

Language: English

Topic: Poisoning and overdose treatments

Subfield: Emergency Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,950