Work

Development of carboximidamide small molecule nanogels as potent antimicrobial functional drug delivery systems

Year: 2025

Type: article

Abstract: . Cytotoxicity studies on human fibroblast cells demonstrated high biocompatibility, with cell viability maintained above 85% at therapeutic concentrations. These findings highlight Cs/PVP nanogels as promising drug delivery systems with dual antibacterial mechanisms, offering improved potency, safety, and potential clinical application against MDR infections.

Source: RSC Advances

DOI: 10.1039/d5ra05150a

Authors: Basmah Almohaywi, Mohammed H. Elkomy, Mohamed A. M. Ali, Ahmed K. B. Aljohani, Mohammed S. Abdulrahman, Mohamed M. Elsebaie, Alaa M. Alhammad, Khadijah A. Aytah, Seba M. Alshehri, Elaaf O. Alharbi, Rama R. Alharbi, Hany E. A. Ahmed

Institutions: King Khalid University, Jouf University, Imam Mohammad ibn Saud Islamic University, Taibah University, Al-Azhar University

Language: English

Topic: Antimicrobial agents and applications

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042

Funder: King Khalid University

Award: G4929924895

OpenAlex ID: W4414664385

FWCI: 1.453

Cites: 52

Cited by: 5

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